You enquired — is psoriasis related to liver?

Contents

Yes, psoriasis can be related to liver function as there is a strong association between psoriasis and non-alcoholic fatty liver disease (NAFLD).

Complete answer

Psoriasis is a skin condition that affects nearly 125 million people globally. While the exact cause of psoriasis is unknown, recent research suggests that there is a link between psoriasis and liver function. In fact, there is a strong association between psoriasis and non-alcoholic fatty liver disease (NAFLD).

NAFLD is a condition where excessive fat builds up in the liver, causing it to become inflamed. This condition is common among people who are overweight or obese, which is also a risk factor for psoriasis. Studies have found that people with psoriasis are more likely to have NAFLD than those without the skin condition.

According to Dr. Alexa Kimball, a dermatologist, “the link between psoriasis and NAFLD is not entirely understood, but it is thought that inflammatory cytokines produced in psoriasis may play a role in the development of NAFLD.”

Interestingly, studies have also shown that treating NAFLD can improve psoriasis symptoms. This is because reducing the amount of fat in the liver can help reduce inflammation throughout the body, including the skin.

In addition to NAFLD, other liver conditions such as hepatitis B and C have been associated with psoriasis. It is important for individuals with psoriasis to monitor their liver function and discuss any concerns with their healthcare provider.

In conclusion, while the link between psoriasis and liver function is not fully understood, there is evidence to suggest that the two conditions are related. It is essential to maintain a healthy weight, monitor liver function, and seek medical attention if necessary. As dermatologist Dr. Mark Lebwohl says, “We remind our patients to be mindful that their psoriasis is not just a skin condition but an overarching systemic disease with potentially serious comorbidities, including liver disease.”

Table:

Liver condition	Psoriasis association
Non-alcoholic fatty liver disease	Strong association
Hepatitis B and C	Associated

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Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837714/
https://www.medicalnewstoday.com/articles/324435
https://www.aad.org/public/diseases/scaly-skin/psoriasis/related-conditions
https://www.psoriasis.org/researchers-discover-link-between-psoriasis-and-liver-disease/

Answer in the video

The video discusses various skin signs that could signify liver disease, the leading cause of health problems globally. Some indications include yellowing skin, spider angiomas, paper money skin, easy bruising and bleeding, nail clubbing, Janthalisma, and beer spots. White nails with a narrow pink band at the tip can point to serious underlying conditions such as liver disease. However, liver spots are small dark areas caused by overactive pigment cells and not related to liver conditions. Fatty liver disease is also a common problem, and viewers are encouraged to check out related videos.

There are alternative points of view

Many psoriasis patients develop liver disease. Here’s what we know about how the conditions are related. Up to 47 percent of psoriasis patients develop nonalcoholic fatty liver disease (NAFLD), a potentially life-threatening condition involving fat deposits in the liver not caused by alcohol abuse.

People with psoriasis may be at a higher risk of developing liver disease. The two conditions can have similar causes, such as systemic inflammation. Liver disease is also a potential side effect of some psoriasis medications.

In general, the more psoriasis you have on your body, the greater your risk to not only have liver disease, but severe liver disease. This lines up with other research that has found that people who had psoriasis on at least 10 percent of their body had nearly double the risk of death.

People with psoriasis have increased inflammation throughout the body, which increases the risk of developing comorbid conditions (more than one chronic disease at the same time). For example, people with psoriasis have a higher prevalence of fatty liver disease compared to the general population.

Liver enzyme abnormalities are common in psoriasis patients and are mostly associated with drugs and NAFLD. Although most cases can be managed by avoiding hepatotoxic medications and close follow up, severe consequences like cirrhosis may develop.

Coherent with previous studies, psoriasis is actually thought to have a potential and intrinsic hepatolesivity. This idea was recently supported by the first mouse-model of hepatitis in imiquimod-induced psoriasis [ 2 ].

Psoriasis is an inflammatory systemic disorder with cutaneous, joint, and other manifestations, including the metabolic syndrome. Liver problems in psoriasis can be: Systemic manifestations and associations of psoriasis — non-alcoholic fatty liver disease (NAFLD), autoimmune hepatitis, primary biliary cholangitis, neutrophilic cholangitis

Psoriasis is a systemic inflammatory disease associated with a variety of comorbidities. It has been shown that psoriasis patients have an increased incidence of nonalcoholic fatty liver disease over controls.

Up to 47 percent of psoriasis patients develop nonalcoholic fatty liver disease (NAFLD), a potentially life-threatening condition involving fat deposits in the liver not caused by alcohol abuse.

Interesting Facts on the Subject

Did you know that, People with psoriasis may be more at risk of developing Parkinson’s disease because of the inflammation in the neuronal tissue. Chronic kidney disease appears to be more common among people with psoriasis.

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What disease is associated with psoriasis?

A comorbidity is a disease or condition that occurs because of or is related to a health condition that you have, such as psoriasis.

Health Conditions Linked to Psoriasis.
Psoriatic Arthritis.
Cardiovascular Disease.
Metabolic Syndrome.
Obesity.
Hypertension.
Dyslipidemia.
Diabetes.

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Can liver problems cause psoriasis?

Response: Studies have found that having certain other forms of liver disease raises your risk of psoriasis, too. This includes: Alcoholic liver disease. Primary biliary cholangitis, an autoimmune disease where your body destroys the bile ducts in your liver.

Can liver problems cause skin conditions?

Chronic liver disease of any origin can cause typical skin findings. Jaundice, spider nevi, leuconychia and finger clubbing are well known features (Figures 1 a, b and Figure 2). Palmar erythema, “paper-money” skin (Figure 3), rosacea and rhinophyma are common but often overlooked by the busy practitioner.

What are symptoms of psoriasis of the liver?

Answer to this: As liver function gets worse, other more commonly recognized symptoms of cirrhosis appear including:

Easy bruising and bleeding.
Yellow tint to your skin or the whites of your eyes (jaundice).
Itchy skin.
Swelling (edema) in your legs, feet and ankles.
Fluid buildup in your belly/abdomen (ascites).

How long can you live with psoriasis of the liver?

Psoriasis of the liver life expectancy can be days to weeks once you reach the final stage.With psoriasis issues, practicing more natural methods from the beginning to treat symptoms can help you to never get to this point.

Can liver detox cure psoriasis?

The answer is: The liver cannot regenerate and heal adequately when bombarded with these damaging substances. Cleansing and regenerating the liver can reduce and even eliminate symptoms of psoriasis. There are many options for liver cleanses on the market.

Who is at risk for developing psoriasis?

Who is at risk of developing psoriasis? There is a genetic link: If one parent has psoriasis, offspring have a 10% chance of developing it, 50% if both parents are affected. However, not everyone with psoriasis has a family member with psoriasis.

Is psoriasis associated with liver disease?

The response is: Background/objectives:Psoriasis patients have a higher risk of liver abnormalities such as non-alcoholic fatty liver disease (NAFLD), drug-induced hepatitis, alcoholic hepatitis and neutrophilic cholangitis, than the general population. Associated liver disease limits therapeutic options and necessitates careful monitoring.

What is the relationship between psoriasis and nonalcoholic fatty liver disease?

Answer: Patients with nonalcoholic fatty liver disease and psoriasis have more severe skin disease and are at higher risk of severe liver fibrosis than patients without psoriasis.

How does psoriasis affect the body?

Response will be: People with psoriasis have increased inflammation throughout the body, which increases the risk of developing comorbid conditions (more than one chronic disease at the same time). For example, people with psoriasis have a higher prevalence of fatty liver disease compared to the general population.

Is psoriasis an inflammatory systemic disorder?

Answer: Psoriasis is an inflammatory systemic disorder with cutaneous, joint, and other manifestations, including the metabolic syndrome. Liver problems in psoriasis can be: Systemic manifestations and associations of psoriasis — non-alcoholic fatty liver disease (NAFLD), autoimmune hepatitis, primary biliary cholangitis, neutrophilic cholangitis